We all experience ups and downs. Some days feel bright and clear. Others feel foggy, heavy, or anxious. When stress, low energy, and lack of focus stack up, your mood suffers. That’s where targeted nutrition can help.
Specific supplements to boost mood can give your brain and body the support they need to feel balanced and resilient again.
At Moodeys, we focus on formulas that support mental wellness from the inside out. Our supplements combine functional herbs, mushrooms, vitamins, and adaptogens—each one chosen for its proven impact on emotional and cognitive health. Let’s look at three of the most effective mood-boosting supplements you can use today.

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1. Ashwagandha (KSM-66®)
Ashwagandha is a powerful adaptogen that helps the body regulate stress. When stress goes unmanaged, it raises cortisol levels and can lead to anxiety, irritability, and poor sleep. Ashwagandha helps lower cortisol and brings the nervous system back into balance.
Clinical studies support these effects. A randomized, double-blind trial published in the Cureus Journal of Medical Science found that Ashwagandha significantly reduced anxiety and improved mood in adults with chronic stress. It also helped with sleep quality and energy levels.
Moodeys uses the patented KSM-66® form of Ashwagandha in our flagship Wake-Up Call. This version delivers full-spectrum root extract with high bioavailability, so you feel the effects more quickly and consistently. Whether you’re dealing with daily stress or emotional fatigue, Ashwagandha is a solid foundation for mood support.
2. Lion’s Mane Mushroom
Lion’s Mane is a functional mushroom that supports the brain’s natural ability to grow and heal. It stimulates the production of Nerve Growth Factor (NGF), which helps form new neural pathways and supports brain plasticity. These changes can help improve mood, motivation, and overall mental clarity.
In one clinical trial published in Phytotherapy Research, Lion’s Mane supplementation significantly reduced depression and anxiety in older adults over a four-week period. Researchers believe it improves how the brain communicates internally, which is essential for emotional regulation.
Lion’s Mane is one of the core ingredients in Wake-Up Call. It helps promote a calm, focused mind and is ideal for people who experience emotional fog, low motivation, or fatigue. Since it also supports long-term cognitive health, it’s a great investment in both present and future wellbeing.
3. Magnesium
Magnesium is a vital mineral that many people lack—especially during stressful periods. It plays a central role in nervous system regulation, muscle relaxation, and serotonin production. Without enough magnesium, you may feel more anxious, tense, or low in energy.
According to research published in Nutrients, magnesium supplementation has shown significant positive effects in people with mild to moderate anxiety and mood imbalance. It works quickly and safely, and when paired with other mood-supporting ingredients, it can have a powerful synergistic effect.
Moodeys includes magnesium in our Rest & Repeat evening supplement. This formula supports relaxation, better sleep, and emotional recovery. Combined with daytime support from Wake-Up Call, it helps complete a 24-hour mood support cycle.
Why Choose Moodeys for Mood Support?
At Moodeys, we’re dedicated to clean, effective supplements that support emotional and cognitive health. Our formulas are:
Clinically backed:
We use science-supported ingredients at proven doses.
Clean and transparent:
No fillers, no artificial additives, and no proprietary blends.
Vegan, non-GMO, and Soil Association certified:
Made in the UK with GMP and ISO certifications.
We create supplements that actually work—without short-term highs or crashes. Whether you’re struggling with stress, mental fatigue, or just want to feel more uplifted throughout the day, our products offer real support for the challenges of modern life.
Final Thoughts: Feel Better Naturally
You don’t have to push through bad moods, low energy, or anxious days on your own. With the right supplements to boost mood, you can support your brain, balance your emotions, and build lasting mental resilience—naturally and safely.
Wake-Up Call and Rest & Repeat from Moodeys offer a simple, effective way to support your mood morning through night. No caffeine. No synthetic stimulants. Just clinically effective ingredients that help you feel more like yourself—every single day.