Ashwagandha supplements are derived from the ashwagandha plant (Withania somnifera), an evergreen shrub native to India and parts of the Middle East. Also called Indian ginseng or winter cherry, this adaptogenic herb has been used in Ayurvedic medicine for thousands of years. Today, it’s gaining popularity for its potential health benefits, supported by a growing number of clinical trials and systematic reviews.

Benefits of Ashwagandha
1. Reduce Stress and Anxiety
Ashwagandha is best known for its ability to reduce stress and anxiety. It acts as an adaptogen, meaning it helps the body manage physical and emotional stress.
A 2022 systematic review and meta-analysis of 12 randomized controlled trials found that ashwagandha significantly reduced stress and anxiety levels compared to placebo (PubMed). Most participants took between 250–600 mg per day for 8 to 12 weeks.
2. Improving Sleep
Ashwagandha may also help with improving sleep quality. In Sanskrit, "somnifera" means "sleep-inducing," and modern studies back this traditional use.
A 2021 meta-analysis showed that adults who took 600 mg of ashwagandha daily for at least 8 weeks experienced better sleep and reduced sleep latency (PLOS ONE).
3. Enhance Athletic Performance
Several studies suggest that ashwagandha can boost physical performance. It may improve strength, endurance, and muscle recovery.
According to a 2020 systematic review, ashwagandha improved aerobic capacity, muscle strength, and cardiorespiratory endurance in both trained athletes and sedentary individuals (NCBI).
4. Support Thyroid Function
Some research shows that ashwagandha may support thyroid hormone levels, particularly in people with hypothyroidism.
It appears to help increase levels of T3 and T4, the main thyroid hormones. However, because of this, it may interact with thyroid medications, leading to possible adverse effects (Cleveland Clinic).
5. Hormonal Balance and Fertility
Ashwagandha may also support testosterone production and male fertility. A few clinical trials have shown improved sperm quality and hormone levels in men with infertility issues (Healthline).
Potential Side Effects
Most people tolerate ashwagandha well when taken as recommended. However, there are some potential side effects:
- Upset stomach
- Nausea
- Diarrhea
- Drowsiness
- Headache
Rare cases of liver toxicity have been reported, especially in people with pre-existing liver conditions (NIH LiverTox). Ashwagandha may also affect blood pressure, blood sugar, and immune system activity.
Drug Interactions
Avoid mixing ashwagandha with:
- Thyroid medications
- Sedatives or sleep aids
- Diabetes medications
- Immunosuppressants
For a detailed list, see this Health.com article.
Who Should Avoid It?
People who should avoid ashwagandha include:
- Pregnant or breastfeeding women
- Individuals with autoimmune conditions
- People with liver or kidney disease
- Those taking medication for thyroid or blood pressure
Always consult your doctor before starting a supplement, especially if you’re on medication.
Additional Effects of Ashwagandha
- Cognitive Support: It may help with memory, focus, and mood.
- Anti-inflammatory: Withanolides in ashwagandha show anti-inflammatory activity.
- Immune Regulation: It may support the immune system by balancing cortisol and cytokines.
These effects are still under study, and not all are supported by large-scale trials yet.
FAQs
How much should I take per day?
Most studies use 300–600 mg daily of a standardized extract. Look for products with 5% withanolides.
How long before I feel results?
You may start noticing improvements in sleep or stress in about 2 to 4 weeks. Some benefits may take 8–12 weeks.
Can I take it long-term?
Ashwagandha appears safe for short-term use. Long-term safety data is limited. Take periodic breaks if using regularly.
Does it help with thyroid function?
Yes, in some cases. But it may over-stimulate the thyroid, especially if you’re already on medication. Use with caution.
Can women take ashwagandha?
Yes. Women may benefit from its stress-reducing and sleep-enhancing properties. However, it’s not recommended during pregnancy.
Final Thoughts
Ashwagandha supplements offer a range of benefits—from reducing stress and anxiety to improving sleep, enhancing physical performance, and possibly supporting thyroid function. These effects are backed by clinical trials, systematic reviews, and centuries of use in Ayurveda.
That said, be mindful of possible adverse effects, especially if you’re pregnant, on medication, or have health conditions. Always talk to your doctor before adding any new supplement.
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